A Facile and Inexpensive Way to Synthesize N‐trifluoromethyl Compounds
نویسندگان
چکیده
Abstract A facile way to introduce CF 3 groups on a large variety of secondary amines has been developed, avoiding expensive and hazardous reagents. The advantage the method could be demonstrated by obtaining crystalline tert ‐butyl 4‐(trifluoromethyl)piperazine‐1‐carboxylate, compound that previously only had obtained as an oil. major problem is extreme sensitivity these compounds towards moisture.
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ژورنال
عنوان ژورنال: ChemistrySelect
سال: 2022
ISSN: ['2365-6549']
DOI: https://doi.org/10.1002/slct.202201803